Studies of semantic variables (e.g., concreteness) and affective variables (i.e., valence and arousal) have traditionally tended to run in different directions. However, in recent years there has been growing interest in studying the relationship, as well as the potential overlaps, between the two. This article describes a database that provides subjective ratings for 1,400 Spanish words for valence, arousal, concreteness, imageability, context availability, and familiarity. Data were collected online through a process involving 826 university students. The results showed a high interrater reliability for all of the variables examined, as well as high correlations between our affective and semantic values and norms currently available in other Spanish databases. Regarding the affective variables, the typical quadratic correlation between valence and arousal ratings was obtained. Likewise, significant correlations were found between the lexico-semantic variables. Importantly, we obtained moderate negative correlations between emotionality and both concreteness and imageability. This is in line with the claim that abstract words have more affective associations than concrete ones (Kousta, Vigliocco, Vinson, Andrews, {\&} Del Campo, 2011). The present Spanish database is suitable for experimental research into the effects of both affective properties and lexico-semantic variables on word processing and memory.