The galvanic skin response (GSR) has provided important scientific insight in a wide range of contexts and has been used in neuroscience research for many decades. It is important for undergraduate students to understand this versatile technique and its application in areas such as Affective, Behavioral, and Forensic Neuroscience. Participants in this study viewed a slideshow containing negative and neutral images selected from the RADIATE and IAPS databases after being connected to a small portable GSR biofeedback monitor. Images were presented for 7-sec on a computer screen followed by a 20-sec blank screen. Each participant's highest GSR response during the 7-sec image presentation was recorded. Participants provided a valence rating, using a 5-point Likert scale, immediately after each image was presented. The mean GSR for images rated as negative was significantly higher than the mean GSR for images rated as neutral. Results were discussed with the class prior to the completion of demographic and activity effectiveness questionnaires. All responses were significant on the activity effectiveness questionnaire. Participants reported a better understanding of the use of GSR in neuroscience, considered this activity a valuable experience, and recommended its use in future classes.